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Combo skill calculator yadda yadda.

Combos in Dragon Age: Inquisition are a 2-step process: First, you inflict a status ailment using a disabler skill. Then, you make the ailing enemy go boom by using a detonator skill.

For example:
An enemy is first hit with Winter's Grasp, gets frozen, and is then hit by someone's Mighty Blow, causing them to shatter.
Freeze + Impact = Shatter

Possible Results of Skill Combos

ImpactPrecisionEldritch
FreezeShatterShatterBasic Combo
ParalyzeDischargeDischargeBasic Combo
SleepRuptureBasic ComboNightmare
StunBasic ComboRuptureWeaken

Character Combo Matrix

Character Disabler Skills/
Available Status Effects
Detonator Skills/
Available Detonations
Available Combo Effects
Inquisitor
Warrior :
Mage :
Rogue :
Warrior :
Mage :
Rogue :
By themselves:
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Cassandra
Warrior :
Warrior :
By themselves:
With Inquisitor :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Sera
Rogue :
Rogue :
By themselves:
With Inquisitor :
With Cassandra :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Dorian
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Blackwall
Warrior :
Warrior :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Cole
Rogue :
Rogue :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Vivienne
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Solas :
With Varric :
With Iron Bull :
Solas
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Varric :
With Iron Bull :
Varric
Rogue :
Rogue :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Iron Bull :
Iron Bull
Warrior :
Warrior :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
Character Disabler Skills/
Available Status Effects
Detonator Skills/
Available Detonations
Available Combo Effects
Inquisitor
Warrior :
Mage :
Rogue :
Warrior :
Mage :
Rogue :
By themselves:
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Cassandra
Warrior :
Warrior :
By themselves:
With Inquisitor :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Sera
Rogue :
Rogue :
By themselves:
With Inquisitor :
With Cassandra :
With Dorian :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Dorian
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Blackwall :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Blackwall
Warrior :
Warrior :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Cole :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Cole
Rogue :
Rogue :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Vivienne :
With Solas :
With Varric :
With Iron Bull :
Vivienne
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :
With Cole :
With Solas :
With Varric :
With Iron Bull :
Solas
Mage :
Mage :
By themselves:
With Inquisitor :
With Cassandra :
With Sera :
With Dorian :
With Blackwall :